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Winner of 1999 Photonic Circle of Excellence Award PicoStar HR FLYER Data Sheet
PicoStar UF: Data Sheet
PicoStar: Data Sheet
Applications:
PUBLICATIONS: Fluorescence Lifetime 3D-resolved investigation of the pH gradient in artificial skin constructs by means of fluorescence lifetime imaging. Measurement of intracellular oxygen levels using fluorescence lifetime imaging microscopy (FLIM) Whole-body fluorescence lifetime imaging of a tumor-targeted near-infrared molecular probe in mice Toward the clinical application of time-domain fluorescence lifetime imaging Sensing cellular function and molecular activity in vivo using fluorescence lifetime imaging microscopy (FLIM) Video rate fluorescence lifetime imaging and fluorescence lifetime endoscopy Fluorescence lifetime imaging with picosecond resolution for biomedical applications Fluorescence lifetime three-dimensional microscopy with picosecond precision using a multifocal multiphoton microscope Imaging fluorescence lifetime heterogeneity applied to GFP-tagged MHC protein at an immunological synapse Treanor B, Lanigan PM, Suhling K, Schreiber T, Munro I, Neil MA, Phillips D, Davis DM, French PM J Microsc. 2005, 217(Pt 1):36-43 Fast excited state intramolecular proton transfer and subnanosecond dynamic Stokes shift of time-resolved fluorescence spectra of the 5-methoxysalicylic acid/diethyl ether complex. Time-resolved fluorescence of the bacteriophageT4 capsid protein gp23 A wide-field time-domain fluorescence lifetime imaging microscope with optical sectioning S. E. D. Webb,Y. Gu, S. Leveque-Fort, J. Siegel, M. J. Cole, K. Dowling, R. Jones, P. M. W. French, M. A. A. Neil, R. Jus¡kaitis, L. O. D. Sucharov, T. Wilson, M. J. Lever REVIEW OF SCIENTIFIC INSTRUMENTS 2002, 73(4), 2002 Protein localization in living cells and tissues using FRET and FLIM High-speed wide-field time-gated endoscopic fluorescence-lifetime imaging pH-dependent regulation of lysosomal calcium in macrophages Time-domain fluorescence lifetime imaging applied to biological tissue Noniterative Biexponential Fluorescence Lifetime Imaging in the Investigation of Cellular Metabolism by Means of NAD(P)H Autofluorescence Picosecond time-gated microscopy of UV-damaged plant tissue Fluorescence lifetime imaging (FLIM) of rhodamine 123 in living cells Imaging fluorescence lifetime modulation of a ruthenium-based dye in living cells: the potential for oxygen sensing Autofluorescence Lifetime Imaging of Cultivated Cells Using a UV Picosecond Laser Diode Fluorescence lifetimes of molecular dye ensembles near interfaces Time-resolved Microspectrofluorimetry and Fluorescence Lifetime Imaging of Hypericin in Human Retinal Pigment Epithelial Cells. Fluorescence lifetime imaging and spectroscopy as tools for nondestructive analysis of works of art Time-resolved DNA-microarray reading by an intensified CCD for ultimate sensitivity G.Valentini, C.D’Andrea, D.Comelli, A.Pifferi, P.Taroni, A. Torricelli, R.Cubeddu, C.Battaglia, C.Consolandi, G.Salani, L.Rossi-Bernardi and G.De Bellis A UV-Visible-NIR fluorescence lifetime imaging microscope for laser-based biological sensing with picosecond resolution P. Urayama, W. Zhong, J.A. Beamish, F.K. Minn, R.D. Sloboda, K.H. Dragnev, E. Dmitrovsky , M.-A. Mycek Applied Physics B: Lasers and Optics 2003, 76(5), 483-496 Fluorescence-lifetime imaging with a multifocal two-photon microscope Fluorescence lifetime imaging with a low-repetition-rate passively mode-locked diode-pumped Nd:YVO4 oscillator Laser-assisted fluorescence microscopy for measuring cell membrane dynamics Herbert Schneckenburger, Michael Wagner, Martina Kretzschmar, Wolfgang S. L. Strauss and Reinhard Sailer Photochemical & Photobiological Sciences, 2004, 3(8), 817 - 822 FLIM/Microfluidics Quantitative Spatial Mapping of Mixing in Microfluidic Systems Quantitative 3D Mapping of Fluidic Temperatures within Microchannel Networks Using Fluorescence Lifetime Imaging. Time-resolved fluorescence imaging of solvent interactions in microfluidic devices Richard K. P. Benninger, Oliver Hofmann, James McGinty, Jose Requejo-Isidro, Ian Munro, Mark A. A. Neil, Andrew J. deMello and Paul M. W. French OPTICS EXPRESS 2005, 13(16), 6275-6285 Properties of microfluidic turbulent mixing revealed by fluorescence lifetime imaging FLIM/FRET IMAGING EPIDERMAL GROWTH FACTOR RECEPTOR PHOSPHORYLATION IN HUMAN COLORECTAL CANCER CELLS AND HUMAN TISSUES Michael Keese, Richard J. Magdeburg, Torsten Herzog, Till Hasenberg, Martin Offerdinger, Rainer Pepperkok, Jörg W. Sturm, and Philippe I. H. Bastiaens J. Biol. Chem., 2005, 280(30) 27826-27831 Fluorescence Resonance Energy Transfer Between Quantum Dot Donors and Dye-Labeled Protein Acceptors Self-assembled nanoscale biosensors based on quantum dot FRET donors Nanosecond fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy to localize the protein interactions in a single living cell Imaging activation of two Ras isoforms simultaneously in a single cell. Time-Resolved Fluorescence Microscopy and Spectroscopy Time-resolved optical imaging provides a molecular snapshot of altered metabolic functionin living human cancer cell models Dhruv Sud, Wei Zhong, David G. Beer, Mary-Ann Mycek OPTICS EXPRESS, 14(10), 4412, 2006 Time-resolved fluorescence imaging of solvent interactions in microfluidic devices Richard K. P. Benninger, Oliver Hofmann, James McGinty, Jose Requejo-Isidro, Ian Munro, Mark A. A. Neil, Andrew J. deMello and Paul M. W. French OPTICS EXPRESS 2005, 13(16), 6275-6285 Near-field imaging by a micro-particle: a model for conversion of evanescent photons into propagating photons Djenan Ganic, Xiaosong Gan, and Min Gu OPTICS EXPRESS 2004, 12(22), 5325-5335 Uranyl sorption onto gibbsite studied by time-resolved laser-induced fluorescence spectroscopy (TRLFS). Detection of U(VI) on the surface of altered depleted uranium by time-resolved laser-induced fluorescence spectroscopy (TRLFS). Baumann N, Arnold T, Geipel G, Trueman ER, Black S, Read D. Sci Total Environ. 2006 Aug 1;366(2-3):905-9 Uranyl sorption onto gibbsite studied by time-resolved laser-inducedfluorescence spectroscopy (TRLFS) Baumann N, Brendler V, Arnold T, Geipel G, Bernhard G. J Colloid Interface Sci. 2005 Oct 15;290(2):318-24. Complex formation of neptunium(V) with 4-hydroxy-3-methoxybenzoic acid studied by time-resolved laser-induced fluorescence spectroscopy with ultra-short laser pulses. Vulpius D, Geipel G, Baraniak L, Bernhard G Spectrochim Acta A Mol Biomol Spectrosc. 2006 Mar 1;63(3):603-8 An EXAFS and TRLFS investigation on uranium(VI) sorption to pristine and leached albite surfaces Walter M, Arnold T, Geipel G, Scheinost A, Bernhard G. J Colloid Interface Sci. 2005 Feb 15;282(2):293-305. An ultrafast time-resolved fluorescence spectroscopy system for metal ion complexation studies with organic ligands Geipel G, Acker M, Vulpius D, Bernhard G, Nitsche H, Fanghanel T. Spectrochim Acta A Mol Biomol Spectrosc. 2004 Jan;60(1-2):417-24 Aqueous solutions of uranium(VI) as studied by time-resolved emission spectroscopy: a round-robin test. Billard I, Ansoborlo E, Apperson K, Arpigny S, Azenha ME, Birch D, Bros P, Burrows HD, Choppin G, Couston L, Dubois V, Fanghanel T, Geipel G, Hubert S, Kim JI, Kimura T, Klenze R, Kronenberg A, Kumke M, Lagarde G, Lamarque G, Lis S, Madic C, Meinrath G, Moulin C, Nagaishi R, Parker D, Plancque G, Scherbaum F, Simoni E, Sinkov S, Viallesoubranne C. Appl Spectrosc. 2003 Aug;57(8):1027-38 Complexation of uranium (VI) by three eco-types of Acidithiobacillusferrooxidans studied using time-resolved laser-induced fluorescence spectroscopy and infrared spectroscopy. Merroun ML, Geipel G, Nicolai R, Heise KH, Selenska-Pobell S. Biometals. 2003 Jun;16(2):331-9. In vivo detection of macrophages in a rabbit atherosclerotic model by time-resolved laser-induced fluorescence spectroscopy. Determination of visible near-IR absorption coefficients of mammalian fat using time- and spatially resolved diffuse reflectance and transmission spectroscopy Fast Excited-State Intramolecular Proton Transfer and Sub-Nanosecond Dynamic Stokes Shift of Time-Resolved Fluorescence Spectra of the 5-Methoxysalicylic Acid/Diethylether Complex Miroslawa Smoluch, Hem Joshi, Arjen Gerssen, Cees Gooijer and Gert van der Zwan J. Phys. Chem. A, 2005, 109, 535-541 Time-Resolved Fluorescence of the Bacteriophase T4 CAPSID Protein GP23 Aike Stortelder, Joost B. Buijs, Jaap Bulthuis, Saskia M. van der Vies, Cees Gooijer and Gert van der Zwan J. Photochem. Photobiol. B, 2004, 78, 53-60 Fast-Gated Intensified Charge-Coupled Device Camera to Record Time-Resolved Fluorescence Spectra of Tryptophan Time-resolved fluorescence microscopy Time Resolved Fluorescence Measurements of Fluorophores Close to Metal Nanoparticles Time-resolved fluorescence imaging in biology and medicine Time-resolved optical imaging through turbid media using a fast data acquisition system based on a gated CCD camera Cosimo D'Andrea, Daniela Comelli, Antonio Pifferi, Alessandro Torricelli, Gianluca Valentini and Rinaldo Cubeddu J. Phys. D: Appl. Phys. 2003, 36, 1675-1681 Time-resolved spectroscopic fluorescence imaging, transient absorption and vibrational spectroscopy of intact and photo-inhibited photosynthetic tissue Philip B. Lukins, Shakil Rehman, Gregory B. Stevens, Doaa George Luminescence 2005, 20(3), 143 - 151 In Vivo NADH Fluorescence Monitoring as an Assay for Cellular Damage in Photodynamic Therapy Brian W. Pogue, John F. Brandsema, Jonathan D. Pitts, Mary-Ann Mycek, Roger D. Sloboda, Carmen M. Wilmot, and Julia A. O’Hara Photochemistry and Photobiology, 2001, 74(6), 817–824 Time-gated autofluorescence microscopy of motile green microalga in an optical trap Photophysical properties of [N] phenylenes C. Dosche, H.-G. Löhmannsröben, A. Bieser, P. I. Dosa, S. Han, M. Iwamoto, A. Schleifenbaum and K. P. C. Vollhardt Physical Chemistry Chemical Physics, 2002, 4(11), 2156 - 2161 Nanoelectropulse-Induced Phosphatidylserine Translocation Combination of Laser-Induced Fluorescence and Diffuse-Reflectance Spectroscopy for the In Situ Analysis of Diesel-Fuel-Contaminated Soils Single Molecule/Quantum dots/Nanocrystals Room-Temperature Ordered Photon Emission from Multiexciton States in Single CdSe Core-Shell Nanocrystals Surface-Enhanced Emission from Single Semiconductor Nanocrystals Coherent spin transport through dynamic quantum dots Stotz JA, Hey R, Santos PV, Ploog KH Nat Mater. 2005 4(8):585-8 Photophysical Aspects of Single-Molecule Detection by Two-Photon Excitation with Consideration of Sequential Pulsed Illumination Fluorescence Quenching of Dye Molecules near Gold Nanoparticles: Radiative and Nonradiative Effects Ultrafast intramolecular energy transfer in single conjugated polymer chains probed by polarized single chromophore Controlled Fluorescence Bursts from Conjugated Polymers Induced by Triplet Quenching Experimental and theoretical studies of the optical and electronic properties of a zinc complex encapsulated in the nanocavities Linewidth-Limited Energy Transfer in Single Conjugated Polymer Molecules Imaging Through Scattering/Turbid Media Time-gated optical system for depth-resolved functional brain imaging Complete-angle projection diffuse optical tomography by use of early photons Gordon M. Turner, Giannis Zacharakis, Antoine Soubret, Jorge Ripoll, Vasilis Ntziachristos OPTICS LETTERS 2005, 30(4), 409 Improved sensitivity to cerebral hemodynamics during brain activation with a time-gated optical system: analytical model and experimental validation Time-gated backscattered ballistic light imaging of objects in turbid water Manuel E. Zevallos, S. K. Gayen, M. Alrubaiee, and R. R. Alfano APPLIED PHYSICS LETTERS 2005, 86, 011115 Time-resolved Mueller matrix imaging polarimetry Fluorescence optical diffusion tomography using multiple-frequency data Localization and quantification of fluorescent inclusions embedded in a turbid medium. Do fluorescence decays remitted from tissues accurately reflect intrinsic fluorophore lifetimes? Quantitative fluorescence lifetime spectroscopy in turbid media: comparison of theoretical, experimental and computational methods Karthik Vishwanath, Brian Pogue and Mary-Ann Mycek Phys. Med. Biol. 2002, 47, 3387-3405 Time-resolved optical imaging through turbid media using a fast data acquisition system based on a gated CCD camera Cosimo D'Andrea, Daniela Comelli, Antonio Pifferi, Alessandro Torricelli, Gianluca Valentini and Rinaldo Cubeddu J. Phys. D: Appl. Phys. 2003, 36, 1675-1681 FINGER-PRINT IMAGING Fluorescence optimisation and lifetime studies of fingerprints treated with magnetic powders Application of fluorescence lifetime imaging (FLIM) in latent finger mark detection Homodyne assisted multistep phase shifting in phase-resolved optical technique for latent fingerprint imaging U. S. Dinish, Z. X. Chao, V. M. Murukeshan, L. K. Seah Opt. Eng. 2004, 43(12), 2831–2832 Formulation and implementation of a phase-resolved fluorescence technique for latent-fingerprint imaging: theoretical and experimental analysis U. S. Dinish, Z. X. Chao, L. K. Seah, A. Singh, and V. M. Murukeshan APPLIED OPTICS 2005, 44(3) 297-304 Fluorescence Lifetime Imaging and Spectroscopy as Tools for Nondestructive Analysis of Works of Art Semiconductor/OLED Characterization Real-time dynamics of the acoustically induced carrier transport in GaAs quantum wires Two-photon diagnostics of stress-induced exciton traps and loading of 1s-yellow excitons in Cu2O N. Naka and N. Nagasawa Phys. Rev. B 65, 075209 (2002) (5 pages) Optical tracking of high-density cooled excitons in potential traps in Cu2O N. Naka and N. Nagasawa physica status solidi (b) 2003, 238(3), 397 - 403 Effects of wandering photons on the excitonic optical signals in Cu2O crystals Bosonic stimulation of cold 1s excitons into a harmonic potential minimum in Cu2O N. Naka and N. Nagasawa Solid State Communications 126 (2003) 523–525 Ultrafast Magnetization/Time-Resolved Kerr Microscopy Nanosecond time-scale switching of Permalloy thin film elements studied by wide-field time-resolved Kerr microscopy D. Chumakov, J. McCord, R. Schäfer, H. Vinzelberg, R. Kaltofen, I. Münch, L. Schultz A. Neudert, J. McCord, D. Chumakov, R. Schäfer, L. Schultz Plasma Spectroscopy/Kinetics/Time-Resolved Spectroscopy Interference between streamers in bunch of streamers A.V. Krasnochub, E.I.Mintoussov, M.M. Nudnova, A.Yu.Starikovskii XXVIIth ICPIG, Eindhoven, the Netherlands, 18-22 July, 2005 Phase resolved optical emission spectroscopy on an industrial confined dual frequency capacitively coupled radio frequency discharge Prospects of Phase Resolved Optical Emission Spectroscopy as a Powerful Diagnostic Tool for RF-Discharges T. Gans, V. Schulz-von der Gathen, H. F. Döbele Contributions to Plasma PhysicsVolume 44, Issue 5-6 , Pages 523 - 528 Spectroscopic measurements of phase-resolved electron energy distribution functions in RF-excited discharges T. Gans, V. Schulz-von der Gathen and H. F. Döbele Europhys. Lett., 2004, 66 (2), 232-238 Determination of quenching coefficients in a hydrogen RF discharge by time-resolved optical emission spectroscopy Time dependence of rotational state populations of excited hydrogen molecules in an RF excited plasma reactor Prospects of Phase Resolved Optical Emission Spectroscopy as a Powerful Diagnostic Tool for RF-Discharges T. Gans, V. Schulz-von der Gathen, H. F. Doebele Contributions to Plasma Physics, 2004, 44(5-6), 523 - 528 Spectroscopic determination of phase and space resolved EEDFs in RF discharges T. Gans, V. Schulz-von der Gathen, H. F. Doebele Fronties on Low Temperature Plasma Diagnostics V, 2003, Bari, Italy ENERGY TRANSFER IN HYPERSONIC PLASMA FLOW AND FLOW STRUCTURE PROPANE-AIR FLAME CONTROL BY NON-EQUILIBRIUM LOW-TEMPERATURE Development of a cathode-directed streamer discharge in air at different pressures: Experiment and comparison with direct numerical simulation S. Pancheshnyi, M. Nudnova, and A. Starikovskii Phys. Rev. E 71, 016407 (2005) Deflagration-to-Detonation Control by Non-Equilibrium Gas Discharges and Its Applications for Pulsed Detonation Engine Investigations on a magnetic neutral loop radio frequency discharge D. O'Connell , D. Crintea , T. Gans , U. Czarnetzki Abstract Link Analysis of L-shell line spectra with 50-ps time resolution from Mo X-pinch plasmas S. B. Hansen , A. S. Shlyaptseva, S. A. Pikuz, T. A. Shelkovenko, D. B. Sinars, K. M. Chandler, D. A. Hammer Phys. Rev. 2004, E 70, 026402 Time-gated Raman Spectroscopy Effective suppression of fluorescence light in Raman measurements using ultrafast time gated charge coupled device camera Raman detection of human macular carotenoid pigments Use of picosecond Kerr-gated Raman spectroscopy to suppress signals from both surface and deep layers in bladder and prostate tissue Maria Consuelo Hart Prieto, Pavel Matousek, Michael Towrie, Anthony William Parker, Mark Wright, Alistair William Ritchie, Nicholas Stone Journal of Biomedical Optics, 2005, 10(4), 044006 (6 pages) LIDAR Contrast enhanced imaging in the sea: Application of the optical transfer function for image reconstruction Frank Ahrenberg, Stefan Harsdorf, Joerg Niehues, and Rainer Reuter Short-pulse range-gated optical imaging in turbid water |  | | |||||||
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minimum gate width: 200ps trigger frequency: up to 110 MHz gain modulation: up to 1 GHz Upgrade: 80ps @ up to 10kHz Accessories: delay unit, delay generator, optical trigger unit, trigger resynchronizer Software: Windows compatible 32 bit DaVis software for camera function and peripheral device control, image processing and analysis.